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The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Indications for the use of interferon

Interferons is a group of protein compounds that are normally found in the human body and are produced by cells in response to the invasion of viruses. In medicine, this substance is used as medicine With combined action. Interferon used as an antiviral, immunostimulatory and antitumor agent.

Indications for the use of this drug are quite extensive. They are conditioned a wide range the action of the drug.
Basically, interferon is used to treat viral or neoplastic diseases. Interferon beta is also used to treat multiple sclerosis. Full list indications can always be found in the accompanying instructions for the drug. They may differ for different dosage forms of interferon.

Interferon alpha is indicated for use in the following cases:

• tick-borne encephalitis;
• chronic viral hepatitis B and C;
• Kaposi's sarcoma ( malignant disease associated with HIV);
• skin ( including melanoma.);
• malignant blood diseases hairy cell leukemia, chronic myeloid leukemia);
• malignant neoplasms of the kidneys;
• prevention and treatment of influenza and SARS ( acute respiratory viral infections);
• for prophylactic immunotherapy.

Beta-interferon is used for the following diseases:

• viral warts ( human papillomavirus);
• chronic hepatitis B and C;
• multiple sclerosis;
• malignant lesions of the mammary glands, uterus, blood, skin.

Interferon for viral hepatitis ( B, C)

Viral hepatitis B and C are one of the main medical problems 21st century. They are characterized by a long asymptomatic course ( more than 6 months), but after several years lead to cirrhosis of the liver and almost inevitable death. Viral hepatitis can also lead to liver cancer. Currently, antiviral drugs are used to treat viral hepatitis ( ribavirin, lamivudine) together with interferon preparations ( Alfaferon, Pegasys, Pegintron).

The use of these drugs is most effective in detecting markers of active replication ( reproduction) virus in liver cells. An indication for the use of these drugs is an increase in the level of hepatic transaminases ( ALT, AST) and the presence of an active inflammatory process in the liver. With a dormant, inactive infection, the effect of the drug will be less pronounced.

The drug can be used in various dosages. Depending on the biochemical indicators of liver damage, low ( 3 million IU 3 times a week), medium or high doses ( 10 million IU daily) interferon. In most cases, the use of this drug gives fairly good results, but it depends on many criteria, including gender, route of infection, strain of the virus, and many others. Average efficiency ( achieving full recovery) from treatment accounts for 45% to 65% of cases.

Interferon for herpes

Herpes infection is one of the most common. About 90% of the world's population are carriers of the herpes simplex virus. The herpes virus family is divided into 8 groups that cause various diseases, from the common chickenpox to shingles. Common manifestations of herpes infection ( vesicles on the skin and mucous membranes filled with serous fluid) imply infection with the herpes virus of the first and second types.

Interferons for herpes are used in the form of ointments or injections, depending on the severity of the disease. It is believed that their efficiency approaches 90%. A fairly common drug in the fight against the herpes virus of the 1st and 2nd type is herpferon ointment. It contains interferon ( 20000 IU/ml) and acyclovir, two substances that combine activity against the herpes virus and lidocaine, which reduces itching, burning and pain in the affected area. The drug is used symptomatically for topical application. This combination is several times more active than conventional acyclovir, in addition, this ointment does not have a resorptive effect ( is not absorbed into the blood and does not give side effects).

Interferon in HIV infection and AIDS. Use of the drug in Kaposi's sarcoma

HIV infection infects cells immune system person. The last stage of HIV infection is AIDS ( acquired immunodeficiency syndrome). It occurs as a result of the depletion of the immune system. AIDS is characterized by the development of infections, malignant tumors and lesions nervous system. All this is not normally found in healthy people. There is currently no cure for HIV infection, but the disease can be controlled with antiretroviral therapy.

Interferon has no effect on the immunodeficiency virus, since the membrane structure of target cells of HIV infection is not regulated by interferons. In addition, at the beginning of the disease, the HIV virus independently stimulates the production of interferons. However, despite this, interferon preparations help to contain infections and the development of tumors. It also prevents cytomegalovirus, Epstein-Barr virus and other infections. Taking this drug is almost mandatory at a late stage of the disease, when the production of natural interferon by the body is significantly reduced.

Kaposi's sarcoma is a multiple malignant neoplasm of the dermis of the skin. It is caused by the herpes virus type 8. The tumor has a red tint due to the presence of blood vessels in it, slightly rises above the skin. Treatment is by injecting interferon directly into the tumor ( 8 million IU every other day). The discovery of Kaposi's sarcoma almost always leads to the diagnosis of AIDS. To date, the survival rate of patients with Kaposi's sarcoma for 5 years in the treatment of interferon is about 70%.

Interferon for conjunctivitis, keratitis and other eye diseases

Eye diseases are very common among the population, their worst prognosis is total blindness. Among inflammatory diseases of the eye, viral and bacterial causes are distinguished. Currently, about 500 viruses are known that can affect various structures of the eye. characteristic clinical picture (conjunctivitis, keratitis) is distinguished by damage to the eyes by the herpes virus, adenovirus, enterovirus.

For the treatment of viral eye lesions, ophthalmologists sometimes prescribe eye drops containing interferon. In the past, drops were prepared immediately before use by mixing powder for injection with saline. Today, there are specially prepared drugs of a combined composition in the form of eye drops ( ophthalmoferon). They can be used for adenovirus and herpetic keratitis, conjunctivitis, even in case of corneal ulceration. This drug is also useful in allergic conjunctivitis.

Oftalmoferon has the following properties:

• antiviral ( main action of interferon);
• antibacterial ( contains boric acid);
• antiallergic;
• decongestant;
• lubrication of the eyeball polymer base mimics the action of an artificial tear).

Interferon in cancer, melanoma and other malignant tumors. Use of the drug in blood cancer

Currently, there is a wide variety of treatments malignant neoplasms. Unfortunately, none of them guarantees sufficient effectiveness against all types of cancer. The use of interferon is now considered mandatory in the treatment of melanoma, kidney cancer and two types of leukemia. It allows you to delay the development of the disease, turning mutant cancer cells into less malignant ones.

Melanoma is the most malignant tumor skin, which gives metastases after a few months of its existence. Interferon was used as an experimental treatment for melanoma in the early 1980s, and today there is not a single successful case without it. The drug is used at a dosage of about 10 million IU daily for a year or more, sometimes until the end of life. Despite this, this drug can significantly increase the five-year survival of patients.

Leukemia is a malignant blood disease in which the bone marrow produces a large number of immature leukocytes. As a result, the body becomes susceptible to infections, the person loses weight, becomes weak and easily tired. Interferon shows the greatest effectiveness in the treatment of hairy cell and myeloid leukemia. Sometimes immunotherapy is used in combination with chemotherapeutic agents.

The effectiveness of interferon in blood cancer is explained by a direct antiproliferative effect, as well as the ability to increase the activity of macrophages and lymphocytes ( immune cells that destroy mutant cells). Great success in the treatment of leukemia is achieved when using the drug for 4 to 6 weeks at a dosage of 3,000,000 IU.

Interferon for papillomas

Papillomas are benign skin lesions. Their appearance in most cases is caused by the action of papillomavirus. Papillomas can appear in large numbers and create numerous inconveniences, including aesthetic ones. Infection with papillomavirus increases the risk of malignant neoplasms. Sometimes the treatment of papillomas can only be done conservatively. In this case, interferon is used in various dosage forms and dosages.

For the treatment of papillomas, the following interferon preparations are used:

• Viferon. Used in the form of a gel, ointment ( locally) and candles ( systemically).
• Intron. It is used systemically in the form of intramuscular injections.
• Roferon. It is administered subcutaneously at 1-3 million IU 3 times a week. The duration of treatment is 1 - 2 months.
• Wellferon. It is administered subcutaneously at 5 million IU 3 times a week.

If the viral nature of warts and papillomas has been proven, the effect of the use of these drugs is very high. After 1 month, subcutaneous or intramuscular injection warts completely disappear in 66 - 100% of patients. This is due to the fact that the use of interferons reduces the rate of reproduction of viral genetic material. The effect of cutaneous application of ointments and gels is not so high. It should be borne in mind that interferon treatment is accompanied by numerous side effects, however, for the conservative elimination of papillomas, this approach is practically the only one.

Interferon in multiple sclerosis

Multiple sclerosis is one of the most common neurological diseases. It has an autoimmune nature and is due to the destruction of the myelin sheath of the nerve fibers of the brain and spinal cord. The disease leads to a significant decrease in the quality of life. It proceeds for a long time and gradually progresses after short periods of exacerbation.

pathogenetic therapy ( directed not at the symptoms, but at the cause of the disease) is carried out by a limited list of drugs. Of these, preparations of beta-interferon are distinguished ( rebif, betaferon). Their action is associated with a change in the balance of the immune system towards anti-inflammatory activity. The effect of the drugs is characterized by inhibition of the growth of leukocytes and the cessation of the attack of the body's own tissues.

The drugs are supplied in 0.5 ml syringes containing 8,000,000 IU active ingredient. It is ready to use, which is very convenient for patients suffering from fine motor skills. The medicine is injected subcutaneously. Treatment lasts for a long period from 6 months to 1 year). Taking the drug provides stabilization of the condition and prevents exacerbations. However, a complete cure for the disease is not achieved in all cases. Changes in the sheath of nerves are usually irreversible.

Interferon for polycythemia

True polycythemia ( Wakez disease) is a disease in which the amount of all cellular elements. It is explained by a mutation in the stem cells of the red bone marrow, from which all the cellular elements of the blood develop. Cytostatics, alkylating agents ( cyclophosphamide) and therapeutic bloodletting ( to reduce blood viscosity - hematocrit). Currently, interferon is used in the treatment of polycythemia.

The therapeutic effect of interferon in polycythemia is due to the suppression of proliferation in the bone marrow, which leads to a decrease in the number of platelets, leukocytes and erythrocytes. Treatment with this drug is long ( lasts more than 6 months), but is quite effective. Between 50 and 90% of patients were completely cured ( achieved complete remission). disadvantage this method is a large number of complications. Approximately one fifth of patients refuse such treatment due to side effects.

Interferon for tick-borne meningitis and encephalitis

Tick-borne encephalitis is a transmissible viral infection that is characterized by damage to the nervous system. Tick-borne encephalitis develops after a tick bite, if it was a carrier of the virus. The disease is characterized by a pronounced pain syndrome, increased muscle tone and activity, and the acquisition of a forced posture. If untreated, the patient dies within a few days.

Treatment tick-borne encephalitis involves the introduction of a specific immunoglobulin as a vaccine after a tick bite. It is ineffective when administered after 24 hours after a tick bite, and is difficult to tolerate. Interferon is also used as a prophylaxis for tick-borne encephalitis, together with or separately from immunoglobulin.

The interferon preparation is used within 5 days after a tick bite 2 times a day ( in the morning and in the evening) for 500 thousand IU. This measure is quite effective in the prevention of tick-borne encephalitis and is safer than the use of immunoglobulin.

Interferon for the common cold and acute respiratory viral infections ( SARS)

The drug can be used in the treatment of SARS and influenza. There are special dosage forms in the form of nasal drops ( gripferon), which are sold without a prescription and help eliminate the main symptoms of colds and flu. The use of the drug accelerates the recovery period by 1 - 2 days. In the treatment of flu and colds, very small doses of the drug are required, which, when released into the blood, do not cause negative side effects.

For the prevention and treatment of influenza, you can use viferon in the form of an ointment ( to lubricate the nasal passages 1-2 times a day). Also for children, it is recommended to use suppositories that have a general effect and prevent systemic intoxication with influenza.

Interferon for bronchitis

Bronchitis is an inflammatory disease that affects the mucous membrane of the bronchial tree. Bronchitis is acute and chronic. Viruses can cause acute bronchitis, but a bacterial infection is much more likely to cause bronchitis. That is why in the treatment of acute bronchitis it is not customary to use interferon and other antiviral agents.

According to studies, bronchitis in children can be caused by certain types of adenovirus and some other viral infections. With the proven viral nature of bronchitis ( which is very hard to do) the correct treatment is the use of interferon. However, in most cases, the traditional treatment regimen for bronchitis is used.

In the treatment of bronchitis, the following groups of drugs are used:

• oral antiseptics;
• in severe cases - antibiotics.

Interferon for toxoplasmosis

Toxoplasmosis is an infection caused by bacteria of the genus Toxoplasma. The infection has a variety of manifestations, it can be acute and chronic, congenital and acquired. The source of infection are pets, especially cats. The disease proceeds with high fever, liver enlargement, headache, vomiting, and convulsions. Toxoplasmosis is only diagnosed by a blood test for specific antibodies. Toxoplasmosis is a bacterial infection, so antibiotics are used to treat it.

The following antibiotics are used to treat toxoplasmosis:

• sulfadiazine;
• spiramycin;

Interferon is not used to treat toxoplasmosis, since the disease is bacterial, not viral in nature. In blood tests, the level of interferon during the disease increases, but after proper treatment and recovery it returns to normal.

Interferon as a prophylactic

Interferon is a drug with a pronounced antiviral and immunomodulatory effect. This leads to its use as prophylactic (flu and SARS prevention). Most often, mothers try to use it for such purposes, protecting children from infections during seasonal peaks in the incidence.

The use of interferon, of course, gives a good preventive effect, however, even in small concentrations, it can cause serious side effects The child has. That is why you need to understand the risks associated with taking this drug and weigh the pros and cons. At the same time, other types of immunostimulants ( for example, anaferon) often have insufficiently proven effect and their use may be useless.

Contraindications to the use of interferon

Interferon is a potent drug. Since this medicine greatly affects the immune and other systems of the body, there are a large number of contraindications to its use. The drug cannot be purchased at a pharmacy without a doctor's prescription, therefore, in consultation with a doctor, it is necessary to exclude all possible contraindications. If they are neglected, you can cause serious harm to your body. The drug is undesirable for pregnant women and young children.
The drug is contraindicated in the following cases:

• heavy cardiovascular diseases (acute myocardial infarction);
• severe liver and kidney disease;
• functional disorders of the nervous system;
• autoimmune hepatitis or other autoimmune diseases ( in addition to multiple sclerosis);
• autoimmune thyroiditis and previous thyroid disease;
• hypersensitivity ( allergy) for the drug.

The drug is used with caution in case of severe lung disease ( in chronic obstructive pulmonary disease), with diabetes mellitus, increased blood clotting. Before using the drug, you must always consult with your doctor or pharmacist.

Interferon for epilepsy

The drug should not be used for epilepsy, depression, severe mental disorders. This drug has an extensive effect on body systems, including the nervous one. It can cause seizures, mood changes, and other unpleasant side effects. In the case of epilepsy, the drug worsens the course of this disease and may provoke its deterioration.

The drug is also not recommended to be taken in conjunction with sedatives, hypnotics, and opioid analgesics. These groups of drugs, in one way or another, affect the state of the nervous system and can also lead to unwanted side reactions.

Interferon in autoimmune diseases

Interferon cannot be used for most autoimmune diseases. This drug has the ability to stimulate immunological reactions, so it can aggravate the course of diseases such as autoimmune hepatitis, thyroiditis and other diseases. The drug can be used exclusively in multiple sclerosis, since this disease has been proven to change immune reactions towards their reduction.

The uncontrolled distribution and use of this drug is prohibited, since this action not only depletes the reserve of the immune system, but can also potentially lead to autoimmune diseases. The drug increases the rate of antigen presentation ( foreign particles) competent cells, however, in the case of an immune error, any tissue of the body may be recognized as a foreign substance.

Precautions before using the drug

Before using this drug, especially with systemic effects ( in the form of injections), it is recommended to pass full examination organism. Particular attention is paid to the general and biochemical analysis of blood. Thanks to these analyzes, hidden diseases of the liver, kidneys, and hematopoietic system can be detected. Taking the drug can adversely affect the condition of these organs.

It is also recommended to periodically repeat the control analysis of peripheral blood parameters, the results of liver enzymes, creatinine, blood sugar levels. At diabetes and hypertension requires an examination of the fundus. Treatment with interferon against the background of chronic heart failure, arrhythmia, myocardial infarction must be carried out under the supervision of a cardiologist.

Can interferon be used during pregnancy?

Interferon is undesirable for use during pregnancy. According to the American Pharmaceutical Quality Assurance Association, this drug may be used if the potential benefit to the mother outweighs the risk to the fetus. Despite this, a number of studies suggest that the incidence of preterm birth and cases of fetal growth retardation is increased when interferon is taken by pregnant women.

This drug can be used as an antiviral and antitumor agent if the woman is not pregnant. After the onset of pregnancy, you can choose safer analogues that will help maintain the health of the fetus and unborn baby.

Can interferon be used in childhood?

There are different opinions about the possibility of using this drug in childhood. Many doctors say that it is impossible to stimulate the immune system in childhood, as this can potentially cause its insufficiency later. In accompaniment to many drugs containing interferon, manufacturers write about the prohibition of its use in childhood. However, there are some dosage forms designed specifically for children.

Interferon in the form of injections is completely prohibited for use in children. One of the drugs that can officially be used in childhood is viferon. This drug is presented in the form of ointments, gels and suppositories. Ointments and gels, when used locally, do not have a resorptive ( systemic) effect and do not lead to side effects. Suppositories can be used for general treatment because the content active substance they are quite small - up to 1 million IU. It should be noted that the effect of using the drug can be obtained only after a few days, so there is not always a need for its use. Before using the drug, you should consult with a pediatrician.

side effects of interferon

Interferon is a drug that has many side effects. It negatively affects almost all human systems and organs. This circumstance is very important for long-term use of the drug as part of course therapy. About 20% of patients stop using it due to the development of side effects. Before using the drug, patients must be informed of possible side effects. If some of them occur, it is possible to correct side effects with other medicines.
Side effects when using the drug occur, as a rule, after injection. Even the right way to use the drug will not help to avoid such phenomena. However, the use of ointments, gels and drops containing this substance usually does not lead to side effects.

When using interferon, side effects and disorders of the following systems and organs are observed:

• Blood and lymphatic system. Sometimes there is a decrease in the number of erythrocytes, platelets and leukocytes due to a decrease in the activity of hematopoietic processes.
• The cardiovascular system. The drug can cause an increase in blood pressure, palpitations, cardiomyopathy.
• Nervous system. Almost all patients taking this drug complain of headache, fatigue. Sometimes his reception is accompanied by depression, convulsions, muscle hypertonicity, emotional instability. Concentration of attention, taste sensations, sleep stability may be disturbed.
• Respiratory system. Bronchospasm and shortness of breath are rarely observed.
• Gastrointestinal system. Rarely, the drug is accompanied by nausea and vomiting. Sometimes there is a violation of the stool ( constipation or diarrhea). In some cases, exacerbation of pancreatitis was noted.
• endocrine disorders. Use of this substance may result in thyroid gland (hypothyroidism, hyperthyroidism, autoimmune thyroiditis ).
• Liver and bile ducts. In laboratory data, there is a temporary increase in the activity of liver enzymes, as well as an increase in the content of fatty acids in the blood. Rarely, taking the drug leads to liver failure.
• urinary and reproductive system. Very rarely, the drug can lead to kidney failure. There may be an increase in urination, prolonged menstrual bleeding in women, impotence in men.
• Musculoskeletal system. Rarely observed muscle pain, joint pain, cramps in lower limbs. The patient may be disturbed by pain in the back, neck, bones.
• Organ of vision. Taking the drug may adversely affect the quality of vision, may occur inflammatory diseases eye, intraocular bleeding while taking the drug. When using the drug, serious cases of retinal detachment have been reported.

Allergic reactions in response to the use of the drug. Formation of antibodies to interferon

allergic reactions ( hypersensitivity) to the drug develops quite rarely. Local skin manifestations urticaria, edema) are a type of allergy. In case of allergy, the drug should be stopped immediately. In the worst case, taking interferon threatens with such dangerous allergic manifestations as Quincke's edema, anaphylactic shock, Stevens-Johnson syndrome.

The study showed that with prolonged use of the drug, antibodies to interferon were found in 1-5% of patients. This suggests that the drug in this case becomes less effective and potentially develops the risk of developing allergic reactions. The formation of antibodies to interferon is most often observed in patients with chronic viral hepatitis.

flu-like syndrome. Fever after taking interferon

Taking this drug in almost all cases is characterized by the development of general reactions. They are grouped together under the name flu-like syndrome, as they have a similar presentation to an infection caused by the influenza virus. This syndrome includes symptoms that are similar to the body's response to intoxication. The most common of these is an increase in temperature ( about 38 degrees). The flu-like syndrome disappears on its own after a few weeks of taking the drug. In the first days, when this syndrome manifests itself most acutely, doctors recommend taking paracetamol ( or other non-steroidal anti-inflammatory drugs) how reliable remedy for its elimination.

Flu-like syndrome from taking interferon includes the following symptoms:

• headache;
• aches and pain in the muscles;
• increase in body temperature;
• general malaise;
• high fatigue;
• chest pain and tissue necrosis at the injection site. If the rules of asepsis and antisepsis are not followed, a post-injection abscess may develop at the injection site.

  Influence of interferon on the thyroid gland. Autoimmune thyroiditis

  Interferons are one of the types of cytokines that have anti-inflammatory and immunostimulatory effects. Cytokines are proteins that regulate the interaction between cells of the immune system. Cytokines play an important role in the development of autoimmune diseases, including autoimmune thyroiditis. Scientists cannot yet explain why the use of interferon of all autoimmune diseases increases the risk of damage to the thyroid gland.

  It has been proven that long-term use of the drug can lead to the destruction of glandular tissue due to the action of one's own immune system. Thyroid disease is manifested by a decrease in the hormonal activity of the thyroid gland ( hypothyroidism) and the detection of antibodies to hormones and thyroid cells in the blood. These symptoms disappear when the drug is discontinued. Patients with a history of thyroid disease should be especially careful when choosing interferon as the main drug.

  Overdose and poisoning with interferon

  No cases of drug overdose have been identified. This drug can be used in very high doses, which is used, for example, in cancer. There are no special events affecting the possibility of continuing treatment, even with a twofold increase in the dose. However, when it is used in such large quantities, the risk of side effects, especially of an allergic nature, increases dramatically. When interferon doses are exceeded, the hematopoietic system is suppressed ( decrease in the number of platelets and leukocytes in the blood). In addition, liver performance deteriorates due to the toxic effect of interferon on the liver.

  Interferon interaction with other medicinal substances

  Interferon usually combines well with other drugs, as serious illnesses it is used in complex therapy. So, with viral hepatitis, it is used in conjunction with ribavirin. With the herpes virus, it is combined with acyclovir. It is also possible to combine interferon with antibiotics, chemotherapy drugs ( for the treatment of neoplasms), anesthetics ( painkillers), anti-inflammatory and antiallergic drugs. At the same time, full-fledged studies on the interaction of interferon with drugs from other groups have not been conducted.

  Theoretical achievements in the field of medicine prove that this substance in large doses inhibits the activity of liver enzymes. It is these enzymes that process most drugs and prepare them for removal from the body. Thus, theoretically, metabolism slows down ( metabolism) for many drugs ( diazepam, propranolol, warfarin, cimetidine and others). Therefore, the use of certain drugs ( as well as alcohol) together with interferon leads to an increase in the neurotoxic effect of these drugs, and can also damage the heart and hematopoietic organs.

  Can I use the drug when driving a car and operating mechanical means?

  At the beginning of the use of the drug, you should beware of driving a car, as well as other mechanical means, since the drug can affect the state of the central nervous system and impair attention. The drug is usually used as part of long-term courses, so subsequently the body adapts to its intake and restrictions on administration vehicles fall away.

  Can I drink alcohol while taking interferon?

  Alcohol is not recommended during treatment with interferon. If interferon is taken in courses, alcohol consumption may be prohibited throughout the course ( from 1 month or more). Regardless of the dosage form of the drug, the effect of the interaction of alcohol and interferon will be unfavorable for the body. This drug increases the toxicity of alcohol in relation to the liver, exacerbation of peptic ulcer may occur, headache, lethargy, tinnitus appear. The interval between taking the medicine and alcohol should be at least 14 hours.

  Prices for interferon in Russian cities

  This drug has a fairly large number of options for dosage forms. It cannot be said that they are affordable, since the cost of drugs containing interferon exceeds the cost of similar drugs. This is due to the complexity of obtaining this substance. Prices for the drug vary in a very wide range. They depend on the manufacturer of the drug ( domestic drugs are much cheaper than foreign ones), on the content of the active substance, on the region of the Russian Federation.

  The cost of interferon preparations in pharmacies of Russian cities
  

  City	Price various drugs interferon
  	Grippferon nasal spray 10 ml 10,000 IU/1ml	Viferon, suppositories 1,000,000 IU, 10 pieces	Oftalmoferon, eye drops 10 ml 10,000 IU/1ml	Reaferon-ES-Lipint Lyophilisate for suspension preparation ( ingestion) 500,000 IU 5 items
  Moscow	325 rubles	490 rubles	306 rubles
  St. Petersburg	311 rubles	529 rubles	347 rubles	659 rubles
  Ufa				680 rubles
  Krasnoyarsk	298 rubles			728 rubles
  Krasnodar	325 rubles	470 rubles	266 rubles	635 rubles
  Permian	307 rubles	578 rubles	449 rubles	808 rubles
  Kazan	335 rubles	515 rubles	313 rubles
  Saratov	305 rubles	479 rubles	306 rubles	656 rubles
  Novosibirsk			318 rubles	718 rubles
  Voronezh	286 rubles		348 rubles

  
  In addition to the cost, the buyer may face another problem - the lack of interferon preparations in pharmacies. Indeed, these drugs are much less common than well-known anti-inflammatory drugs. This can be explained by the fact that only a limited number of preparations containing interferon have been certified in Russia. Therefore, on the shelves of pharmacies you can find this medicinal substance in the form of nasal or eye drops, ointments, gels or suppositories. The drug for injection may not be available on the general market at all, even with a prescription, due to its lack in pharmacies. In this case, it has to be ordered from abroad or purchased in specialized medical centers where these dosage forms are available.

  Can I buy drugs containing interferon in pharmacies without a prescription?

  Preparations containing interferon in the vast majority of cases cannot be purchased at pharmacies without a doctor's prescription. Their use is associated with a large number of side effects, and long-term use can disrupt the normal functioning of the immune system. That is why taking the drug without a prescription threatens with serious complications and health problems.

  On the other hand, there is a category of interferon drugs ( e.g. influenza), which can be purchased without a prescription. This is because they contain a very small amount of the active substance, which acts locally and does not change its total content in the blood. However, before using them, you should consult your doctor about the need to use these drugs. Perhaps you should turn to safer and more affordable analogues.

  Preparations containing Interferon alfa-2
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Viferon (Viferon)	candles 150 thousand IU	10	Russia, Feron	165- (average 236↘) -272	729↘
  Viferon (Viferon)	candles 500 thousand IU	10	Russia, Feron	242- (medium 342↗) -431	740↘
  Viferon (Viferon)	suppositories 1 million IU	10	Russia, Feron	379- (medium 492↗) -632	701↘
  Viferon (Viferon)	suppositories 3 million IU	10	Russia, Feron	652- (middle 782↗) -883	711↘
  Viferon-ointment	40 thousand IU / g - 12g	1	Russia, Feron	112- (average 171↗) -225	552↘
  	powder for injection 1000ME 4 doses	5 and 10	Russia, Microgen	64- (average 83↗) -121	303↘
  Interferon human leukocyte dry	powder for injections 0.5ml	10	Russia, Biomed	67- (average 84↗) -113	159↘
  Interferon human leukocyte dry	powder for injections 1ml	10	Ukraine, Biolek	70-(medium 74)-116	113
  Interferon human leukocyte dry	powder for injections 2ml	2 and 10	Russia, Biomed	66-(middle 83)-137	250↘
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Alfaferon (Alfaferone)	solution for injections 3 million IU/ml 1ml	1	Italy, Alpha Wassermann	1134-(average 1390)-2050	48↗
  Alfaferon (Alfaferone)	solution for injections 6 million IU/ml 1ml	1	Italy, Alpha Wassermann	3100-3565	3↘
  	ointment 5g	1	Russia, Vector	No	No
  Interferon human leukocyte liquid	solution of 2 thousand IU in 2 ml	5	Russia, Biomed im. Mechnikov	55- (average 67↘) -86	11↘
  Interal	powder for injection 3 mlnIU	5	Russia, GNIIOCHP	No	No
  Interferon human leukocyte dry	candles 40 thousand IU	10	Russia, Biomed	No	No
  Interferon human recombinant alpha-2	ointment 2g	1	Russia, Vector	No	No
  Intron A (Intron A)	solution for injection 18mlnIU 1.2ml 6 doses	1	Ireland, Shering Plow	5990-(average 6000)-7899	39↘
  Intron A (Intron A)	solution for injections 18mlnIU 3ml 6dose	1	Belgium, Schering Plow	5990- (medium 6090↗) -7886	27↘
  Intron A (Intron A)	solution for injection 25mlnIU 2.5ml 5 doses	1	Ireland, Shering Plow	7000- (average 8450↗) -9456	4↘
  Intron A (Intron A)	solution for injections 30 mln IU 1.2 ml 6 doses	1	Ireland, Belgium Schering Plough	9500- (average 10850↘) -11399	3↘
  Viferon-ointment	40 thousand IU / g - 10g	1	Russia, Feron	No	No
  Viferon (Viferon)	gel 36 thousand IU / ml - 10 ml	1	Russia, Feron	No	No
  Products containing a combination of Interferon alfa-2 and human immunoglobulin
  Common forms of release (more than 100 offers in Moscow pharmacies)
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Kipferon (Kipferon)	candles (suppositories) rectal and vaginal	10	Russia, Alpharm	550- (average 757↗) -1166	608↗
  Preparations containing Interferon alfa-2a
  Common forms of release (more than 100 offers in Moscow pharmacies)
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Infagel (Infagel)	gel and ointment 10 thousand IU / g - 2 g	1	Russia, Vector	81-(medium 102)-127	288↘
  Infagel (Infagel)	gel 10 thousand IU / g - 3 g	1	Russia, Vector	87-(medium 111)-128	128↘
  Reaferon-EC-lipint	powder for suspension for oral administration 250 thousand IU	5	Russia, Vector	410- (average 540↗) -675	166↗
  Reaferon-EC-lipint	powder for suspension for oral administration 1 million IU	5	Russia, Vector	589- (average 967↗) -1200	150↘
  Reaferon-EC-lipint	powder for suspension for oral administration 500 thousand IU	5	Russia, Vector	449- (middle 745↗) -1885	209↗
  Rare forms of release (less than 100 offers in Moscow pharmacies)
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Infagel	gel 10 thousand IU / g - 5 g	1	Russia, Vector	92- (average 130) -149	52↘
  Roferon-A	solution for injection 3 mlnIU in a cartridge	1	Switzerland, Hofmann-La Roche	1499-2600	77↗
  Roferon-Pen	syringe pen	1	Switzerland, Hofmann-La Roche	1710	1
  Preparations containing Interferon alfa-2b
  Common forms of release (more than 100 offers in Moscow pharmacies)
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Altevir	solution for injection 3 mlnME	1 and 5	Russia, Pharmapark	for 1 piece:525- (average 939↗) -1189 ; for 5 pcs: 939- (average 1096) - 1254	194↘
  Genferon	candles 500 thousand IU	10	Russia, Biocad	240-(medium 423)-644	182↘
  Genferon	suppositories 1 million IU	10	Russia, Biocad	390- (average 456↘) -824	696↘
  Genferon Light	suppositories interferon 125 thousand IU + taurine 5 mg	10	Russia, Biocad	145- (average 222↗) -750	669↘
  Genferon Light	suppositories interferon 250 thousand IU + taurine 5 mg	10	Russia, Biocad	179- (medium 281↗) -412	510↘
  Genferon Light	dosed nasal spray 1 dose - interferon 50 thousand IU + taurine 1 mg - 100 doses	1	Russia, Biocad	197- (average 270) -439	416↘
  Giaferon	candles 500 thousand IU	10	Russia, Vitafarma	240-644	182↗
  Grippferon	drops 10 thousand IU in 1 ml - 10 ml	1	Russia, Firn M	225- (average 276↗) -311	290↘
  Lifeferon (Lifferon)	powder for injection 5 mlnIU	5	Russia, Vector	720-(middle 1775)-2902	663↘
  PegIntron	powder for injections 100mcg	1	Belgium, Schering Plow	5490- (average 7280↘) -11100	108↘
  PegIntron	lyophilized powder. for cooking injection solution 120mcg	Singapore, Sharing Plow	1	5196- (average 7400↗) -11200	138↗
  Rare and discontinued forms of release (less than 100 offers in Moscow pharmacies)
  Name	Release form	Packing, pcs	Country, manufacturer	Price in Moscow, r	Offers in Moscow
  Altevir	solution for injection 5 mlnME	5	Russia, Pharmapark	1352 (middle 1651) -2001	99↘
  Altevir	solution for injections 10mlnME	5	Russia, Pharmapark	384-556	2↘
  Altevir	solution for injection 1 mlnME	5	Russia, Pharmapark	556-1395	2↘
  Alfarona	powder for injection and for local application 3 million IU	5 and 10	Russia, Pharmaclone	for 5 pcs:900- (average 1049) -1665 ; for 10 pcs: 890- (average 1039) - 2160	76↘
  Alfarona	powder for injection and topical application 5 mlnIU	5 and 10	Russia, Pharmaclone	1050-1500	53↗
  Alfarona	nasal powder 50 thousand IU	1	Russia, Pharmaclone	No	No
  Genferon	candles 250 thousand IU	10	Russia, Biocad	215- (average 295↗) -405	73↗
  Grippferon	drops 10 thousand IU in 1 ml - 5 ml	1	Russia, Firn M	225- (average 274↗) -310	17↘
  Lifeferon (Lifferon)	powder for injection 1mlnIU	5	Russia, Vector	468- (average 529↗) -1255	45↗
  Lifeferon (Lifferon)	powder for injection 3 mlnIU	5	Russia, Vector	855-(average 1100)-2300	50↘
  PegIntron (PegIntron)	powder for injection 50mcg	1	Belgium, Schering Plow	5000- (average 7735) -14390	59↘
  PegIntron (PegIntron)	powder for injection 80mcg	1	Belgium, Schering Plow	5200- (average 6955↗) -11200	65↘
  PegIntron (PegIntron)	powder for injections 150mkg	1	Belgium, Schering Plow	5668- (average 7659↘) -11039	71↗
  Realdiron (Realdiron)	powder for injection 3 mlnIU	5	Lithuania, Biofa	3200- (average 3500↘) -3550	36↘
  Realdiron (Realdiron)	powder for injection 6mlnIU	5	Lithuania, Biofa	4500- (average 5290↘) -5899	6↘

  Viferon - instructions for use. Prescription drug, information intended for healthcare professionals only!

  pharmachologic effect

  Human recombinant interferon alfa-2 preparation. It has pronounced antiviral, antiproliferative and immunomodulatory properties.

  The complex composition of the drug causes a number of additional effects. Due to the content of ascorbic acid and tocopherol acetate in the preparation, the specific antiviral activity of interferon alpha-2 increases, its immunomodulatory effect on T- and B-lymphocytes increases, the level of immunoglobulin E normalizes, and the functioning of the endogenous interferon system is restored. In addition, ascorbic acid, alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane-stabilizing, and regenerating properties.

  It has been established that when using Viferon in the form of suppositories, there are no side effects that occur when parenteral administration interferon preparations, and antibodies are not formed that neutralize the antiviral activity of interferon.

  Pharmacokinetics

  Data on the pharmacokinetics of the drug Viferon in the form of rectal suppositories are not provided.

  Indications for use of the drug VIFERON

  • as part of the complex therapy of infectious and inflammatory diseases in children, incl. newborns and premature infants: influenza, SARS (including those complicated by bacterial infection), pneumonia (bacterial, viral, chlamydial), meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes infection, cytomegalovirus infection, enterovirus infections, candidiasis, including visceral, mycoplasmosis);
  • as part of the complex therapy of chronic viral hepatitis B, C, D in children and adults, incl. in combination with the use of plasmapheresis and hemosorption, in chronic viral hepatitis of a pronounced degree of activity and complicated by cirrhosis of the liver;
  • as part of complex therapy in adults, incl. in pregnant women with urogenital infection (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, human papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis); primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate course, incl. urogenital form;
  • as part of the complex therapy of influenza and other acute respiratory viral diseases(including complicated by a bacterial infection) in adults.

  Dosing regimen

  As part of the complex therapy of infectious and inflammatory diseases in children:

  Newborns (including premature babies with a gestational age of more than 34 weeks) are prescribed Viferon 150 thousand IU, 1 suppository 2 times a day with an interval of 12 hours. The course of treatment is 5 days.

  Premature newborns with a gestational age of less than 34 weeks are prescribed Viferon 150 thousand IU, 1 suppository 3 times a day with an interval of 8 hours. The course of treatment is 5 days.

  The recommended number of Viferon courses for various infectious and inflammatory diseases in children, incl. newborns and premature babies: influenza, SARS, incl. complicated by a bacterial infection - 1-2 courses; pneumonia (bacterial, viral, chlamydial) - 1-2 courses; sepsis - 2-3 courses; meningitis - 1-2 courses; herpetic infection - 2 courses; enterovirus infection- 1-2 courses; cytomegalovirus infection - 2-3 courses; mycoplasmosis, candidiasis, incl. visceral - 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.

  As part of the complex therapy of chronic viral hepatitis B, C, D in children and adults:

  In chronic viral hepatitis in children, the dose of the drug depends on age. For children under the age of 6 months, Viferon is prescribed at a dose of 300-500 thousand IU per day; at the age of 6 to 12 months - 500 thousand IU per day. Children aged 1 to 7 years - 3 million / m2 of body surface area per day, over the age of 7 years - 5 million / m2 per day. The calculation of the dose of the drug for each specific patient is carried out by multiplying the dose recommended for a given age by the body surface area calculated from the nomogram to calculate the body surface area by height and weight according to Harford, Terry and Rourke, divided by 2 injections, rounded up to the dosage of the corresponding suppository. The drug is used 2 after 12 hours for the first 10 days daily, then 3 weeks. every other day for 6-12 months. The duration of the course is determined by clinical efficacy and laboratory parameters.

  Children with chronic viral hepatitis of a pronounced degree of activity and liver cirrhosis before plasmapheresis and / or hemosorption are shown to use Viferon 1 suppository 2 times a day with an interval of 12 hours for 14 days (children under the age of 7 years - Viferon 150 thousand IU, children over 7 years old - Viferon 500 thousand IU).

  Adults with chronic viral hepatitis are prescribed Viferon 3 million IU, 1 suppository 2 times a day with an interval of 12 hours for 10 days daily, then 3 times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory parameters.

  As part of complex therapy in adults, incl. in pregnant women, with urogenital infection (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, human papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis), with primary or recurrent herpetic infection of the skin and mucous membranes (localized form, mild and moderate course, including urogenital form).

  Adults with the above infections, except for herpes, are prescribed Viferon 500 thousand IU, 1 suppository 2 times a day after 12 hours. The course is 5-10 days. According to clinical indications, therapy with Viferon in the form of rectal suppositories can be continued with an interval between courses of 5 days.

  In case of herpetic infection, Viferon is prescribed 1 million IU, 1 suppository 2 times a day after 12 hours. The course of treatment is 10 days or more in case of recurrent infection. It is recommended to start treatment immediately when the first signs of skin and mucous membrane lesions (itching, burning, redness) appear. In the treatment of recurrent herpes, it is desirable to begin treatment in the prodromal period or at the very beginning of the manifestation of signs of relapse.

  In pregnant women with urogenital infection (including herpetic) in the II trimester of pregnancy (starting from week 14) - Viferon 500 thousand IU 1 suppository 2 times a day with an interval of 12 hours for 10 days, then 1 suppository 2 once a day with an interval of 12 hours 2 times a week - 10 days. Then, after 4 weeks, prophylactic courses of the drug Viferon 150 thousand IU are carried out, 1 suppository every 12 hours for 5 days, the prophylactic course is repeated every 4 weeks. If necessary, it is possible to conduct a treatment course before childbirth.

  As part of the complex therapy of influenza and other acute respiratory viral diseases (including those complicated by a bacterial infection) in adults:

  Apply Viferon 500 thousand IU, 1 suppository 2 times a day with an interval of 12 hours daily. The course of treatment is 5-10 days.

  Side effect

  Allergic reactions: rarely - skin rash, itching.

  Contraindications to the use of the drug VIFERON

  • hypersensitivity to the components of the drug.

  The use of the drug VIFERON during pregnancy and lactation

  The drug is approved for use from the 14th week of pregnancy.

  It has no restrictions for use during lactation.

  special instructions

  Possible allergic reactions are reversible and disappear 72 hours after the end of the drug.

  Overdose

  Data on an overdose of the drug Viferon is not provided.

  drug interaction

  Viferon is compatible and well combined with all drugs used in the treatment of the above diseases (including antibiotics, chemotherapy drugs, corticosteroids).

  Terms of dispensing from pharmacies

  The drug is dispensed by prescription.

  Terms and conditions of storage

  The drug should be stored out of the reach of children, protected from light at a temperature of 2° to 8°C. Shelf life - 2 years.

  Interferon nasal drops are prescribed for colds. Interferons themselves are endogenous proteins. Such proteins are produced by blood cells, which in turn are affected by viral infections. Nose drops with interferon help well with acute respiratory diseases. As soon as the main substance penetrates the body, it is its own interferons that begin to be actively produced. Such substances already help to fight viruses.

  Composition of the drug and pharmacological action

  Spray or drops of interferon have almost the same composition. As for the drops, they are produced in the form of a solution in liquid form. The drug has several spectra of action, namely antiviral, as well as immunomodulatory. Instructions for use suggests that the agent may have an antitumor effect, as it helps to stimulate macrophages.

  Interferon drops in the nose help to significantly increase resistance human body, directly to the penetration of malicious viruses. In addition, if used correctly, the drug helps to block the reproduction of viruses.

  Instructions for use: main indications

  The drug is prescribed as a treatment for viral diseases, which in turn affect the respiratory tract.

  Doctors can pee in the complex treatment to drip drops of Interferon for chronic hepatitis B or C. In addition, the drug is prescribed for such diseases. For example:

  • Fungal mycoses.
  • Chronic myeloid leukemia.
  • As complex treatment with reticulosarcoma.
  • It is prescribed for kidney cancer, as well as for hairy cell leukemia.
  • Most often, a nasal solution or spray is prescribed as a treatment for the common cold. But, a runny nose with such a remedy can be cured only if it has a viral etiology.

  What is the difference between drops and spray?

  There is practically no difference between spray and drops. The composition of the drug is the same. But, the release form is different. Drops are prescribed most often for adults. For young children, it is more convenient to use the drug in the form of a spray. The dispenser helps to quickly distribute the drug over the nasal mucosa.

  Interferon in drops: the main contraindications for use

  The drug can not be used by everyone. In the main instructions that are attached to the package for the drug, you can read who should not take the drops.
  Of the main contraindications, the patient's increased sensitivity to the composition of the drug is noted.
  In addition, you can not use the drug in the treatment of severe mental disorders as well as chronic depression.

  Important! Before using drops or spray, you should consult your doctor. If the drug is used in combination therapy with antiviral drug Ribavirin, complications may occur. Of the complications, violations in the work of the kidneys are noted. Epilepsy is also considered a reason not to use the drug.

  Instructions for use

  The dosage is prescribed only by the doctor, based on the severity of the disease, as well as on the age of the patient. The standard dosage regimen for eye infections is 2 drops every 2 hours. Hen treatment lasts for 6 days.

  With a runny nose, the drug is prescribed 2 potassium in each nasal cavity. Drip 2-3 times a day, depending on the nature of the rhinitis. The course of admission is individual, but does not exceed 10 days. If drops or spray are not brought positive result, can prescribe the same drug only in the form of an ointment. It contains additional components that help to quickly fight viruses.

  The tool can be used not only as a treatment, but also as a preventive measure. For the prevention of acute respiratory infections, it is enough to drip 1 drop into each nasal cavity 2 times a day.

  Side effects

  Use the drug only after consulting a doctor. If you do not follow the correct intake, or there are contraindications for use, side effects may occur.

  Most often there is fever, severe headache, loss of appetite, nausea.
  In rare cases, side effects in a patient may include disturbances in consciousness, diarrhea, dryness in the nasal cavity, as well as hypotension or arrhythmia.

  additional information

  The drug is dispensed from a pharmacy without a prescription from a doctor. The shelf life of the drug is 2 years.

  Important! It is necessary to store drops in a hard-to-reach place from children, and from direct sunlight.

  Cost: from 90-130 rubles.

  Analogues of the drug Interferon

  The most common analogues of this tool, directly according to the ATX level 4 code:

  • Roferon A;
  • Lipoferon;
  • Intron-A;
  • Interferon alpha-2b human recombinant;
  • Intrek;
  • Viferon.

  Remember, analogues of any of the above remedies may have additional spectra of action, have a larger list of contraindications and side effects, as well as a different course and dosage of medication.

  Before buying an analogue, it is necessary to consult a doctor in order to avoid complications, and also not to aggravate the general condition.

  "Interferon" is presented in the form of white, yellow or pale pink ampoules with a dry powder or solution with an activity of up to 1000 IU. It is a mixture of proteins produced by leukocytes of donor blood under the provoking effect of foreign proteins. The drug is aimed at neutralizing viruses that have entered the body and fighting infected cells. In rare cases, one can observe side effects drug: skin rash, nausea, headache, chills. "Interferon" is contraindicated only in case of individual intolerance, autoimmune diseases, acute myocardial infarction, renal and hepatic failure. With prolonged use of the drug, it is very important to control the composition of the blood and liver function.

  In what cases is Interferon effective?

  The drug is used to prevent and treat viral diseases, including complex forms of influenza. In addition, it is part of the complex therapy for candilla, tick-borne encephalitis, hepatitis B and various oncopathologies, including in AIDS patients.

  Prophylactic doses of the drug

  "Interferon" begins to be used when there is a threat of infection with a virus and continues until this danger persists. The drug is administered in equal dosage to adults and children from three years of age by nasal instillation, inhalation or spraying. The ampoule with the drug is opened strictly before use. Purified or cooled boiled water is added to the powder to the mark corresponding to 2 ml. The resulting contents of the ampoule are gently stirred until a clear and slightly opalescent suspension is obtained. Storage of the resulting suspension is allowed for 1 day at temperatures up to +15 °C. The drug is dripped 5-6 drops into each nostril 2-3 times a day. The interval should not be less than 6-7 hours. When spraying, 0.25 ml of solution is injected with the same frequency.

  How to use the drug for treatment

  The drug is usually used for early stage disease at the onset of symptoms. It is administered in equal dosage to children and adults by inhalation or instillation. The first method is considered the most effective. For one patient, the contents of three ampoules are sufficient, which is dissolved in 9-10 ml of water with a temperature of up to 37 ° C. For instillation and spraying, the contents of the ampoule are dissolved in 2 ml of water and 5 drops are injected into each nostril. It is advisable to carry out the procedure at least 5-7 times a day. Course duration - 2-3 days.

  In this article, we will talk about one of the effective antiviral and immunostimulating drugs. We are talking about human leukocyte interferon. We will analyze the properties of the drug, indications for its use, instructions for use, etc.

  Characteristics of the drug

  Leukocyte human interferon ( international name- interferon alfa) is available in two forms - a solution for inhalation and intranasal use and dry lyophilized powder (sometimes compressed into tablets). The liquid form has a shade from colorless to light pink, dry - from white to pinkish.

  Interferon leukocytic human (Interferon leukocytic human) is a complex of proteins that are synthesized by leukocytes of donor blood under the influence of an interferon inducer virus. They are cleaned by ultra- and microfiltration method.

  Analogues of this immunomodulatory drug:

  • "Lokferon".
  • "Inferon"
  • "Nazoferon" and others.

  The tool can be used in combination with other medicines. The drug is dispensed without a doctor's prescription, valid for 2 years from the date of manufacture. It must be stored in a place protected from light, cool (2-8 degrees above zero). Keep away from children!

  Average prices per human leukocyte interferon relatively low. So, in most pharmacies, a pack of 10 ampoules of the drug will cost 80-120 rubles.

  The composition of the drug

  1 ml of liquid human leukocyte interferon contains:

  • Interferon alpha - 1000 IU.
  • Sodium chloride - 0.09 mg.
  • Sodium dihydrophosphate dihydrate - 0.06 mg.
  • Sodium hydrogen phosphate dodecahydrate - 0.003 mg.
  • Distilled water for injection - about 1 ml.

  Pharmacological properties

  This immunomodulatory drug belongs to pharmacological group cytokines. Its properties are as follows:

  • Immunostimulation - makes the immune response stronger.
  • Immunomodulation - normalizes the immune status.
  • Antibacterial action - the fight against different kind mixed infections.
  • Antiviral action - helps the body resist diseases such as herpes, influenza, adenovirus diseases.
  • Anti-inflammatory, antitumor effect.

  

  Dry and liquid agent is non-toxic, sterile, harmless when administered through respiratory tract. In this case, the use of powder for injection is prohibited.

  Indications for use

  Human leukocyte interferon is used both for the prevention of acute viral infections, and for the treatment of early forms of diseases with initial symptoms.

  Indications can be divided into three main groups:

  • Intranasal application: preventive measures and treatment of SARS, influenza.
  • Parenteral use: condyloma acuminata, hepatitis B and C, non-Hodgkin's lymphoma, malignant melanoma, multiple myeloma, renal carcinoma, Kaposi's sarcoma in AIDS patients (not currently ill acute infections), hairy cell leukemia, mycosis fungoides.
  • Rectal application: therapy of chronic and acute viral hepatitis.

  

  Also, the drug will be effective for:

  • chronic myeloid leukemia;
  • primary and secondary thrombocytosis;
  • transitional stage of chronic granulocytic leukemia, myelofibrosis;
  • reticulosarcoma;
  • multiple sclerosis.

  Contraindications

  Instructions for use of human leukocyte interferon indicate the following contraindications to the use of the drug:

  • Epilepsy.
  • Violation of the functions of the central nervous system.
  • Violation of the functions of the kidneys and liver, hematopoietic system.
  • organic heart disease.
  • Chronic hepatitis in persons whose recent treatment has consisted of immunosuppressants.
  • Diseases of the thyroid gland.
  • chronic hepatitis.
  • Cirrhosis of the liver with signs of liver failure.
  • Pregnancy and lactation.
  • Allergy.
  • Increased individual sensitivity to the active ingredient - interferon alpha, as well as to all drugs of protein origin, to chicken meat and eggs.

  

  The drug is dangerous to take in the following cases:

  • The expiration date has expired.
  • The integrity of the package is broken.
  • There are no markings on the container.

  Dosage and application

  Instructions for use of human leukocyte interferon prescribes:

  • For children under 3 years of age, administer the drug only intranasally (spray, instillation).
  • Children from 3 years old, adults are additionally allowed inhalation.

  Intranasal application. The ampoule with the medicine is opened immediately before use. Then chilled boiled or sterile distilled water is added to it strictly up to the line of 2 ml per capsule. The product is gently shaken until completely dissolved.

  The drug is instilled into the nose with a syringe without a needle or a medical pipette. Another way is spraying: you can use both a third-party sprayer and the one that comes with the preparation. The nozzle is put on a syringe without a needle, then brought close to the nasal passage or going into it by about 0.5 cm. Spraying occurs by pressing the syringe plunger. The patient should sit with his head thrown back.

  Dosage of the drug:

  • Prevention: apply throughout the danger of infection. Instillation - 5 drops, spraying - 0.25 ml into each nasal passage. The manipulation is carried out up to 2 times per day with an interval of at least 6 hours.
  • Treatment: at the first signs of the disease. 5 drops or 0.25 mg in each nostril. The procedure is repeated up to 5 times a day with an interval of 1-2 hours.

  Human leukocyte interferon is administered to children and adults in the same doses.

  

  Inhalation. Inhalation use is considered more effective. For him, you need to purchase an inhaler from any manufacturer. One procedure requires the contents of three capsules, which should be dissolved in 10 ml of water heated to 37 degrees. In this way, the drug is administered through the mouth and nose twice a day for 2-3 days.

  Injection is prohibited!

  Side effects

  When using this immunomodulatory drug, the following side effects are possible:

  • From the gastrointestinal tract: change taste sensations, dry mouth, flatulence, constipation, vomiting, diarrhea, nausea, loss of appetite. In rare cases, a violation of the liver.
  • From the side of the central nervous system: ataxia, drowsiness or sleep disturbance, impaired consciousness, depression, nervousness.
  • From the side of the heart and blood vessels: arrhythmia, arterial hypotension.
  • Dermatological effects: skin rash, slight alopecia, erythema, dry skin.
  • Flu-like syndrome: weakness, fever, myalgia, headache.
  • Other: granulocytopenia, feeling of weakness, lethargy, weight loss, visual disturbances, dizziness.

  

  special instructions

  It is worth using the product with caution when:

  • Recent myocardial infarction.
  • Myelodepression, changes in blood clotting.
  • Elderly patients who have been diagnosed with CNS side effects when using high doses of the drug. It may even be worth interrupting the treatment.
  • Patients with hepatitis C should be screened for TSH levels before treatment. Only when normal interferon therapy can be started. In other cases, there may be a violation of the functions of the thyroid gland.
  • Combination with opioid analgesics, hypnotics, sedatives.

  Human leukocyte interferon is an effective immunostimulating anti-infective agent. It has a number of features of use and contraindications, therefore, before use, familiarity with the instructions is necessary.

  A drug for restoring age-related tissue structure deficiency