Cardiology

AST and ALT are elevated on a Biochemical Blood Test - what does this mean. The norm and causes of deviation of ast and alt in women What does ast mean in a blood test

AST and ALT are elevated on a Biochemical Blood Test - what does this mean.  The norm and causes of deviation of ast and alt in women What does ast mean in a blood test

Human blood is unique in its composition. It includes a lot of different elements that are necessary for a healthy and long life. Deviations from the norm in the readings of at least one component indicate malfunctions in the body and development various diseases. What are ALT and AST, what do their indicators indicate and why is it so important to know them. Blood test ALT, AST - the norm in women.

What are these elements

The first studies of the transamination reaction were carried out in 1937. Transamination is an intermolecular interaction that denotes the transfer of an amino group without the formation of ammonia. ALT and AST are enzymes that are responsible for transporting individual components from one atom in the human body to another. ALT transports aspartate (an amino acid), AST transports alanine. These enzymes are present in all tissues and their amount in the blood must be stable. In the event that their content begins to exceed the norm, you need to sound the alarm, because this indicates that a disease is developing in the body.

Deep enzymatic studies began to be carried out relatively recently. For the study, you need to use special equipment. To prevent errors, the analysis should be carried out by an experienced specialist, and at the slightest suspicion of an oversight, the study is repeated. A biochemical blood test for AST and ALT, the norm in women is less than in men and depends on the age of the patient. Over the years, in women, these figures may decrease.

Why is this survey necessary?

Deviation in AST and ALT levels in a blood test may indicate serious violations internal organs. An increase in ALT in the blood in women indicates serious liver damage. This enzyme lives in large quantities in the human liver and enters the bloodstream as a result of natural discharge. If the liver is damaged, the blood begins to flow a large number of this substance. The norm of ALT for women is from 20 to 40 units per liter of blood.

It should be borne in mind that transaminase may increase when taking certain medications.

Increased AST - what does it mean? These blood test results indicate that the muscle has been damaged. It can be a muscle injury, but most often this indicator signals problems in the heart muscle. Enzyme analysis in myocardial infarction will determine the violation within a few hours after the onset of the development of the pathology. The norm of AST in the blood in women is in the range of 34-36 units. We can talk about pathology if the level of AST is exceeded dozens of times.

What pathologies can we talk about with deviations from the norm

What is ALT in a women's blood test? Alanine transaminase levels can increase as a result of many factors. A separate increase in alt in women several times may mean the development of the following pathologies:

  • Hepatitis.
  • Cirrhosis of the liver.
  • Oncology of the liver.
  • Mononucleosis.

When is the AST blood test elevated? A separate increase in AST in women signals heart disease, especially after 50 years. It is for this reason that this study is indicated to be carried out by women after 50 years of age annually. Also, an increase in the blood test in women of these enzymes can signal a combination of diseases of the heart and liver.

Third-party factors such as:

  • Strong physical activity.
  • Reception of certain groups of medicines.
  • Injuries, burns, operations.
  • Pregnancy and childbirth.

It is worth noting that we can talk about the development of pathologies only when transaminases in the blood exceed the norm tenfold. Minor deviations in AST and ALT in women are most often provoked by third-party factors. It is for this reason that you do not need to panic if your ALT and AST in the blood are different from the norm. In this case, the study will need to be repeated after a certain period of time.

Definition of indicators

Today in our country there is no single scale for determining the units of enzymes in the blood. Each laboratory has its own standards and indicators, so in one center the level can be calculated in units / l, and in the other in mmol / l. Therefore, deciphering the analysis on its own is impossible.

Only an experienced doctor will be able to correctly decipher the results of your tests and prescribe additional examinations if necessary.

When deciphering, it is necessary to take into account not only the gender, but also the age of the patient, as well as the presence of possible provoking factors. Therefore, the normal rate of enzymes in different healthy people can vary significantly and it is completely unacceptable to judge your health based on the results of acquaintances and friends. The table of norms of indicators is used by doctors, taking into account all these factors.

How to reduce performance

It is possible to reduce the level of ALT in the blood, as well as AST, only by eliminating the causes of the deviation. So, for example, if elevated ALT detected after drug treatment, they must be canceled and after some time the analysis should be repeated. But if the cause was a disease of the internal organs, it is possible to lower the rates only after serious treatment.

Prevention is of particular importance in this regard. If you have chronic diseases of the liver, pancreas, gallbladder or heart, you need to carefully monitor your health. These diseases are well treated today. But therapy must be comprehensive. Medication alone will not help you. Treatment must be accompanied by a special sparing diet and the rejection of bad habits. People at risk should have their enzymes tested every 6 months. If the rate of ALT and AST will increase, urgent action must be taken.

When to check

Many dangerous diseases liver and heart in the early stages are completely asymptomatic. For their early diagnosis, an analysis for transaminases is quite suitable. Seek immediate medical attention if you experience any of the following symptoms:

  • Unreasonable periodic weakness.
  • Prolonged loss of appetite.
  • Frequent nausea and vomiting.
  • Stomach ache.
  • Yellowness of the skin and sclera of the eyes.
  • Change in color of urine to dark brown.
  • Lightening of feces.
  • Skin itching in conjunction with other symptoms.

How is biochemistry done?

Today, this analysis can be taken at any clinic and for a fee. medical center. Women's analysis is no different from children's or men's. For everyone, there are certain rules that must be observed, namely:

  • Blood sampling is carried out from a vein in the elbow bend.
  • The analysis should be taken in the morning on an empty stomach.
  • Fasting should be at least 8 hours.
  • Need to give up physical activity before blood sampling.
  • Stress can affect the results of the analysis.
  • No smoking 60 min. Before the blood draw.
  • You need to give up alcohol and fatty foods 12 hours before analysis.
  • If possible, refuse to take medication, if this is not possible, you need to warn the doctor about it.

If medication is the cause

Often it is in women over the age of 50 that the elevation of enzyme levels occurs from prolonged treatment. medicines. These can be hormones, antibiotics, or chemotherapy drugs. If you notice that the enzyme increases after taking medication, you need to contact your doctor to correct therapy. You can replace toxic drugs with gentle ones that will not be harmful to your body.

With the development of high technology, medicine can determine more and more problems in the body by a blood test. Today, despite the fact that enzyme analysis began to be carried out quite recently, it is already used everywhere. Without this study, not a single operation is performed today, it is prescribed to patients with various ailments. Thanks to this, doctors can now quickly and painlessly identify many diseases on early stage, which means to conduct timely treatment and prevent dangerous conditions.

In contact with

Alanine aminotransferase, or ALT, and aspartate aminotransferase, or AST, are enzymes found in body cells that are involved in amino acid metabolism. They are located only in the cells of organ tissues, and enter the bloodstream only when the cell decays due to traumatic injuries or pathologies.

Types of diseases

Excessive content of ALT indicates the development of the pathology of the organ, in the cells of which there is its largest amount. The causes of an increase in alanine aminotransferase are liver pathologies. Feelings of discomfort and pain sensation in the area of ​​the right hypochondrium, diarrhea, icteric staining of the skin and mucous membranes, flatulence, bitter belching are signs of an increase in ALT. When conducting a blood test, an increase in the level of bilirubin joins the increased ALT and AST when hepatitis develops. More often, an increase in the content of ALT indicates the occurrence of other diseases. The concentration of ALT is directly dependent on the severity of the pathology.

The necrotic process in the heart muscle causes the release of these enzymes into the blood. Their increased content in serum also indicates the development of other cardiopathologies: insufficiency, inflammation of the heart muscle. Additionally, the reasons for the increase in the concentration of ALT in the serum may be present in the body injuries, which are associated with damage to muscle tissue, and pancreatitis.

If ALT and AST blood test (decoding) showed higher normal indicators less than twice, it is necessary to organize observation and 2-fold examination. This tactic is optimal for patients.

ALT and AST blood test - decoding for some diseases

A slight increase in transferases is indicative of non-alcoholic fatty liver damage, including "fatty liver", non-alcoholic steatohepatosis, viral hepatitis B chronic form.

A moderate increase may exist with viral or alcoholic inflammation of the liver and various chronic diseases liver with or without cirrhosis.

Elevated levels are typical of severe acute hepatitis, toxic or drug necrosis, shock, or hepatic ischemia.

An excessively high level (more than 2000-3000 U / l) exists with an overdose of acetaminophen and when using the drug in alcohol-dependent patients, with shock and / or hepatic ischemia.

It should be noted that since ALT is located in erythrocytes, it is necessary to prevent their decay when preparing serum for analysis. ALT may decrease if serum is stored for several days.

The role of medicines, herbs and other substances

Careful history taking and interpretation of laboratory results are important to detect drug-induced increases in transferases. Similar liver damage is detected in 1-2% of cases of liver inflammation in a chronic form. They are associated with the use of antibiotics, antiepileptic drugs, hydroxymethylglutaryl-CoA reductase inhibitors, non-steroidal anti-inflammatory drugs and drugs for the treatment of tuberculosis.

Most easy method to determine the dependence of the increase in aminotransferases with some kind of agent - to cancel it and observe the level of enzymes. Without canceling the remedy, this dependency cannot be determined.

When a person is sick, it is almost impossible to make a correct diagnosis and prescribe competent treatment without tests. Often you do not need to go through all existing laboratory research. To date, it is enough for a doctor to study the decoding of a biochemical blood test and the indicators of the ALT and AST norms in an adult or a child in order to understand the whole nature of the disease. One of the most important indicators in this analysis is the level of liver enzymes - ALT and AST. Changes in the permissible limits of these blood components may indicate serious diseases.

What is AST

AST, in scientific circles, aspartate aminotransferase - a protein - a "builder" responsible for the synthesis of amino acids in the body. In addition, he is an active participant in all metabolic processes of the body.

AST is a component that has its own specifics. It is concentrated exclusively in tissues, and its detection in serum is an alarming sign. The highest concentration of this enzyme is concentrated in the heart, kidney, muscle tissues, part is located in the nervous tissues. As soon as the analysis reveals the presence of this element in the biomaterial, then the pathology begins where AST is found the most. Accordingly, its level in the blood begins to rise. Most often, diseases are associated with pathologies of the heart or liver. All changes in the level of AST can only be detected by a biochemical blood test.

A few words about ALT

Together with the AST indicator, a biochemical blood test reveals the level of ALT, alanine transferase, an enzymatic protein synthesized in the human liver. The main percentage of ALA is found in the liver and kidneys, while a small amount is found in the heart tissues.

This enzyme is involved in the metabolism of amino acids. Thanks to this, general immunity increases, the production of lymphocytes actively begins, and it controls the production of sugar. By nature, it is arranged in such a way that this hepatic transaminase behaves more actively in the male body than in the female.

If the level of ALAT rises, then most likely we have a problem with the kidneys, liver, lungs or pancreas.

AST and ALT are indicators that are considered and interpreted in conjunction with each other.

Indications for analysis

It happens that in order to make a diagnosis, the attending physician needs only an analysis of ALT and AST. Biochemistry is prescribed in the following cases:

  • pregnancy;
  • with existing pathology of the heart and liver;
  • control of prescribed therapy;
  • suspected cardiac infarction;
  • damage abdominal cavity or chest;
  • when taking strong drugs that have a detrimental effect on the heart and liver. For example, in the treatment of HIV or major depression.

What can analyzes reveal?

The AST test and the ALT blood test are the most important tests. Any deviation from the norm is considered a pathology. AST and ALT monitor the body's response to various stimuli.

From the side of the liver, it can be:

  1. Liver damage from alcohol or excessive or prolonged use of medications.
  2. Cirrhosis of the liver, including alcoholic.
  3. Hepatitis of any type

The indicator of the level of ALAT in the blood may vary depending on the degree of physical exertion on the body, the presence of burn areas, ischemic damage, and injuries of any type. Based on the results obtained, the doctor prescribes the appropriate treatment.

Biomaterial collection rules

Absolutely any analysis requires careful preparation. Only in this way can you be sure of the reliability of the results obtained.

Since ALT and AST are the most important indicators of liver function, it is very important to follow a diet for at least a few days before donating the biomaterial.

Do not eat salty, fatty, spicy. This can not only worsen your score, but also significantly increase blood clotting, which may not allow for an examination, as required.

  • The analysis is given strictly on an empty stomach with a sustained hungry pause of 8 hours or more.
  • Refrain from smoking for at least a few hours before giving the sample.
  • Drink only plain water. Sweet drinks will blur the real picture.
  • Alcohol is prohibited.
  • Limit the use of eggs, cottage cheese, any dairy products.
  • Eliminate physical overwork on the eve of the study.
  • Tune in a positive way, calm down, and only after that head to the treatment room.
  • It is not necessary to analyze the level of AST and ALT, if the day before that you underwent an ultrasound examination, an X-ray, visited a physiotherapy room, and did a fluorography.

Deciphering analyzes

AST. Norm and deviations

In an ideal biochemistry analysis, the AST value should be as low as possible. This means that no health problems have been identified to date. However, it is important to understand that the rules for this study is a relative concept. They vary by age and gender.

A sign of the disease can only be high rates. We are not talking about a low level of ASAT. Even if you see 0 units / l in the decryption, then you should not worry. As a deviation and a sign of the disease, this is not considered. The only thing that can indicate a decrease in ALT and AST in the blood is a lack of B vitamins. A decrease in indicators is also characteristic of pregnancy, which is due to the bearing of the baby and the restructuring of the hormonal background.

Doctors divided the severity of the situation into three types:

  • moderate, when the excess is 5 times;
  • medium form - 10 times;
  • severe form, in which the level of AST is overestimated by 10 times or more.

The following pathologies are possible:

ALT norms

Norms of ALT, as well as ASAT, depend on the gender and age of the patient. The study in children is carried out taking into account the age.

It is important to surrender that all these norms are relative. So the result can be increased when taking certain drugs, for example, aspirin, paracetamol, or when using oral contraceptives. The same false result will give you the use of valerian, echinacea, excessive physical activity for non-compliance with the rules for the delivery of biomaterial.

Preliminary diagnosis

Making a diagnosis for a patient is a responsible and difficult task, since the choice of treatment that ensures the health and life of a person depends on it. Usually, in order to identify the disease, the patient has to take a lot of tests, undergo examinations.

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But most of the information about the health status of an adult and a child is found out during a biochemical analysis of the patient's blood. And if a person suffers from liver diseases, such an examination is the main one for determining the exact disease.

A blood test for biochemistry is performed in all patients in whom the doctor suspects the presence of serious illnesses liver. The main parameters in this study are alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The norm of these indicators will tell if there are dysfunctions in the organ, damage to its tissues and other pathologies that affect the functioning of the body as a whole.

In fact, AST and ALT are enzymes that are part of the cells of the main hematopoietic organ of an adult and a child. Aspartate aminotransferase ensures the flow of certain metabolic processes necessary for the breakdown and neutralization of many harmful substances. In addition to the liver, AST is found in tissue cells of such organs as the heart muscle, kidneys, nerve fibers, and skeletal muscles. Responsible for AST and metabolic processes amino acids in the body of a child and an adult.

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The rate of AST in the blood is low, because with healthy organs, only those liver cells that die as a result of natural processes enter the bloodstream. If, as a result of any disease or injury, liver cells are damaged, then the rate of AST in the blood increases dramatically.

The next liver enzyme, alanine aminotransferase (ALT), is also important for making an accurate diagnosis, and performs functions similar to AST in the body of men and women. It is a type of protein responsible for the correct catalysis of amino acids. The highest concentration of ALT is observed in the cells of the liver and kidneys, a small amount is found in muscle tissues and the heart. Both ALT and AST are located directly inside the cells, which means that their presence in the blood is possible only when the tissues of the main organs containing them are destroyed.

What does the enzyme test say?

An experienced doctor will be able to make a preliminary diagnosis already at the first examination. If the patient is suspected of having liver disease, then a blood test for AST and ALT will be required. The transcript of the study will indicate whether there is an excess of permissible standards and how large it is.

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If the increase in enzymes is strong, then the disease has been progressing for a long time and the organs do not function at full strength. The rate of AST and ALT is increased only in pathologies that destroy the tissues of the liver and kidneys. This is typical for many ailments, which can be divided into groups according to the main pathological processes, i.e., an excessive level of AST and ALT is observed when:

  • body poisoning;
  • the presence of a viral infection;
  • cell-destroying diseases.

Intoxication (poisoning) of the body occurs as a result of poisoning with alcohol, toxic drugs, medicines, narcotic substances. Viruses and infections provoke the development of serious diseases such as hepatitis various kinds. The most severe disease that affects the liver and destroys its cells is cirrhosis.

In addition, an increase in AST and ALT occurs with strong physical overstrain (lifting loads, playing sports, etc.), as a result of a mechanical violation of the integrity of the tissues of internal organs, if the patient has received severe body burns.

An increase in enzymes in the body is determined using a biochemical blood test in men, women and children.

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In order for the decoding of the analysis to be as accurate as possible and reflect the true picture of the state of health of an adult or child, it is necessary to take the analysis correctly. Blood sampling is preceded by simple preparation, and the analysis itself is performed on an empty stomach in the morning. The night before, you need to give up heavy and fatty foods, any physical activity, and alcoholic beverages. In the morning before going to the clinic, it is forbidden to drink any drinks other than pure water and smoke. Only if these rules are followed, a biochemical blood test will be as accurate as possible.

Deciphering the results

After blood sampling, laboratory assistants perform a series of necessary procedures and determine the indicators of the parameters of interest. All of them fit into a special form, which indicates:

  • personal data of an adult or a child;
  • date and time of blood sampling;
  • the main indicators of the composition of the biological fluid;
  • the norm of blood flow components;
  • quantitative indicators of the studied components.

Although at first glance at the form it becomes clear whether there is an increase in certain enzymes, it is not necessary to draw independent conclusions about a possible diagnosis.

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The interpretation of the results obtained is carried out only by an experienced specialist, a doctor who issued a referral for examination.

The norm of ALT and AST has differences by gender and age. So, in women, the rate of enzymes is lower than in the representatives of the stronger sex, because they are more physically active. The norm of ALT and AST for them is from 45 to 47 U / l, and in women the figure should not be higher than 35 U / l. The rate of enzymes in the blood of a child also depends on his age. In a newborn child of the first year of life, the ALT norm is 56 U / l, and AST is 58 U / l. From one year to four, these figures are 29 and 59 U / l, respectively, and at the age of four to seven years, 29 and 48 U / l. In a child, before the onset of puberty, enzymes should not exceed 37 and 44 U / l. In adolescents, these parameters converge (as in adults) and amount to 37-39 U / l.

The parameters of the main liver enzymes, unlike most other blood parameters, do not change during pregnancy in women. A slight increase is possible in the second trimester of pregnancy, in all other cases, the analysis will indicate damaged tissues of the internal organ.

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In some laboratories, not only the amount of the enzyme in the blood is determined, but also their ratio, and therefore the decoding indicates the result of the analysis in the form of a coefficient.

What the results will tell

An increase in the levels of transferases in the blood of men and women indicates possible problems with the heart (ischemia, myocardial infarction). If the analysis shows a decrease in the permissible level of enzymes, then this is the first sign of the development of infectious hepatitis.

A feature of enzymes is their localization, that is, they are located in the cells of certain organs, which greatly facilitates the diagnosis of pathologies of these same organs. As soon as the analysis of a child or an adult shows a deviation from the norm of these enzymes, the attending physician can easily make an accurate diagnosis, just by taking an anamnesis and examining the patient. Additional examination methods will help determine the exact affected organ, but biochemical analysis will tell you where to “look for” the disease.

Also, a biochemical blood test, including indicators of these enzymes, can be used as a control of the condition and functioning of the heart and kidneys.

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Early detection of an increase in performance, even a slight one, can help prevent an impending heart attack or kidney failure. The fact that myocardial infarction is already close will be indicated by an excess of parameters by two or more times. Elevated ALT and viral hepatitis, but only during it incubation period, then it starts to decrease.

A decrease in the norms indicated in the analysis is possible with a deficiency of B vitamins. This condition in medicine is called pyridoxine. While waiting for a baby in women, pyridoxine is the norm, but only in the middle of pregnancy, in another period, treatment is required.

What affects the level of transferases in the blood

The level of alanine aminotransferase in the blood of an adult or a child depends on how severe the form of viral hepatitis that has entered the body. The more actively the virus multiplies, the weaker the immune system, the stronger and faster the liver cells are destroyed. And the more enzymes enter the bloodstream of men and women, where they are found during clinical studies.

In a state where the patient's liver is almost completely destroyed, the analysis shows a five-fold excess of the allowable norms of transferases in the blood.

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Having carried out a biochemical study of blood, it is possible to identify the disease at the very beginning of its development, when the virus has just entered the body and has not yet had time to become active. At this stage, there are no manifestations of the disease, so it is very difficult to diagnose the disease. Deciphering the results will help not only to detect the pathology of a particular organ, but also to clarify the stage of development of the disease.

The level of transferases in the blood is primarily affected by pathologies such as:

  • cirrhosis of the liver;
  • malignant tumor;
  • hepatitis of any form;
  • violation of the integrity of liver cells as a result of damage by toxins or drugs.

In addition to diseases of the liver itself, other diseases can also increase the rate of transferases in the body. This inflammation of the pancreas (pancreatitis), acute heart failure, myocardial infarction, burns of large areas of the body, bone tissue death. An increase in enzymes is also possible with serious psychological trauma, in shock states.

If treatment is not carried out and liver cells are not restored, there comes a time when the organ undergoes almost complete necrosis.

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Before donating blood fluid to the level of transaminases, it is important to properly prepare for the analysis and familiarize yourself with the ALT norm in men and women. After all, alanine aminotransferase is a very important element that helps to determine the existing pathologies.

ALT is a marker enzyme for the liver, which belongs to the class of enzymes. Its amount is measured in units per liter of blood fluid. Transferase is responsible for the exchange of aminocarboxylic acids and serves as a catalyst for chemical reactions.

The protein structure is found in the tissues of the following organs:

  • lungs;
  • spleen;
  • excretory organs;
  • myocardium.

The ALT enzyme is of endogenous origin and is essential for the proper functioning of the body.

Its role is quite large:

  • increases the speed of the metabolic process;
  • strengthens the defenses;
  • provides the body with strength and energy;
  • promotes the production of lymphocytes.

Detection of the concentration of Alat is a common diagnostic method that helps to identify diseases of the liver and blood vessels. Mandatory analysis of biochemistry for people suffering from obesity and diabetes. It also allows you to control the course of the therapeutic course, showing the success of the drugs used.

How the study is done

The blood fluid of the venous system is taken for study before lunch. A person should not eat anything before the diagnosis. More than eight hours must have elapsed since the last meal. The day before the procedure, you can not drink alcohol, eat fatty and fried foods. It is recommended to reduce active loads.

Also, you should not take a biochemical analysis after the following procedures:

  • x-ray;
  • colonoscopy;
  • physiotherapy.

Stop taking 10-14 days before medications. If this is unacceptable, the study makes a note about the treatment and dosage of drugs.

When deciphering biochemistry, the level of aspartate aminotransferase (AST) is also taken into account. There is a Ritis scale, which determines the proportions of two structures: alanine aminotransferase (ALT) and aspartate aminotransferase.

Normally, their ratio is 1.33. The error is no more than 0.42.

If, when dividing AST by ALT, a number less than 1.33 is obtained, this is a sign of a painful deviation in the external secretion gland, if higher, it is a symptom of a cardiac disease. So the de Ritis coefficient helps to make a more accurate conclusion regarding a particular patient.

ALT norm in women and men

In the stronger sex, the concentration of transaminases is higher due to better endurance and greater muscle mass. However, men are more likely to suffer from bad habits, eat poorly, face stress and nervous strain.

Therefore, the stronger sex is more susceptible internal pathologies, which give themselves the excess of ALT. In women, the process involving a specific substance does not proceed so quickly.

Thus, the following figures are considered acceptable indicators:

  • the minimum rate of ALT in the blood of women is thirty-one units per thousand milliliters of blood, the maximum is thirty-five;
  • the lowest threshold for men is forty-one units, the maximum is forty-five.

The slightest deviations from the norm by a couple of units are allowed. After fifty years, alanine aminotransferase is increased due to the deterioration of the metabolic process.

In women who are carrying a fetus, the norm is from thirty to thirty-two units. The concentration of the substance varies depending on the trimester. The reason for this reaction is hormonal changes in the body.

Especially rises transaminases in the first and last three months of embryo development. Then its performance increases by two to three times. If the figure is exceeded ten times, this indicates the presence of an ailment. The norm of the catalyst in the blood in young children and adolescents differs from the permissible limits in adults.

The accuracy of the result depends on the following parameters:

  • equipment manufacturer;
  • diagnostic method;
  • laboratory materials.

The final value should be judged by a specialist. Self-diagnose an illness based on laboratory analysis it is forbidden.

Alanine aminotransferase increased - what does it mean

An increased number of ALT in liquid tissue means a violation of the normal functioning of the body. This usually indicates liver problems. Moreover, the higher the concentration of transaminases, the more neglected the disease.

Indications for the diagnosis of ALT are some signs:

  • pain on the right side of the chest;
  • general malaise;
  • lack of desire to eat;
  • dark urine;
  • light feces;
  • yellowing of the skin and eyeballs.

Timely detection of an increase in the concentration of an element will make it possible to eliminate alarming signs and correctly diagnose in order to prescribe high-quality therapy.

Causes of an increase in the enzyme in the blood

An increase in the level of the catalyst may be associated with certain pathological processes:

  1. Hepatitis. It is a hepatic inflammation that causes a modest excess of the level of the substance.
  2. Steatosis. A pronounced growth of the protein structure is observed in steatohepatitis.
  3. Pancreatitis. A strong deviation from the norm indicates an exacerbation of inflammation of the pancreas.
  4. Myocarditis. Along with an increase in the protein structure, shortness of breath and severe fatigue are present.
  5. Clinical form of ischemia. The disease manifests itself as a result of impaired blood flow and causes tissue necrosis.
  6. Oncological disease. Often the result of hepatitis.
  7. Cirrhosis. The disease usually does not have a bright clinical picture.
  8. Muscle degeneration. With it, the indicators of the substance can increase by 7-8 times.

Analysis of the biological fluid shows an increase in ALT immediately after taking ethanol-containing drinks and with alcohol dependence. There are other reasons for the increase in ALT, which are provoked by external factors.

These include:

  • taking estrogens, anabolics, contraceptive pills;
  • too heavy loads;
  • nervous exhaustion;
  • taking niacin;
  • drug addiction;
  • chemical therapy;
  • trauma;
  • poor nutrition (drinking soda, fast food).

These factors provoke a modest increase in the marker enzyme in cells.

What to do when ALT in the blood is elevated

In case of deviation from the ideal designation, it is necessary to carefully examine the body using MRI, CT, ultrasound. The sooner the diagnosis is made, the better the prognosis will be.

The following medications are usually taken to reduce the catalyst in liquid tissue:

  • Tykveol;
  • Progepar;
  • Hepatosan;
  • Karsil.

These drugs protect the liver from destruction and regenerate damaged tissues. In addition to taking medication, it is recommended to adhere to a special diet, excluding spicy, fried and fatty foods from the diet. It is forbidden to get involved in pickles, pickled foods, smoked meats and sausages. It is important to remove strong tea and coffee from the diet, it is worth excluding alcohol and other bad habits.

As additional measures, it is permissible to use decoctions and infusions from the following plants:

  • mint;
  • thyme;
  • milk thistle;
  • immortelle;
  • dandelion;
  • corn silk;
  • chamomile.

It is important to talk to your doctor before starting self-medication. In order not to miss the development of serious pathologies, a biochemical blood test from a vein should be taken 1-2 times a year.